Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects
نویسندگان
چکیده
منابع مشابه
Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects
BACKGROUND In a standard two-stage SMART design, the intermediate response to the first-stage intervention is measured at a fixed time point for all participants. Subsequently, responders and non-responders are re-randomized and the final outcome of interest is measured at the end of the study. To reduce the side effects and costs associated with first-stage interventions in a SMART design, we ...
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ژورنال
عنوان ژورنال: BMC Medical Research Methodology
سال: 2016
ISSN: 1471-2288
DOI: 10.1186/s12874-016-0202-7